Plenary 1:
Exploring the Multiverse of Healthcare Through HTA: Diverse Perspectives, Unified Outcomes

Panelists

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Dr. Simon Fifer

Director of Research and Innovation
HTAi Patient and Citizen Involvement in HTA Interest Group (PCIG)
Community and Patient Preference Research (CaPPRe)

Dr. Simon Fifer is Director of Research and Innovation at Community and Patient Preference Research (CaPPRe) and on the Advisory committee at the Patient Voice Initiative (PVI). He specializes in studying human decision-making using choice-based measurement techniques, with a particular focus on understanding patient preferences in healthcare settings. Simon is on the editorial board for the journal The Patient and also co-chairs the Patient Preference Project Subcommittee (PPPS), part of HTAi’s Patient and Citizen Involvement Group. The current focus of the committee is on the integration of patient preference data in health technology assessment (HTA) processes. Simon has a PhD in Choice modelling from the University of Sydney.

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Dr. Eri Hoshino

Head, International Division
Centre for Outcomes Research and Economic Evaluation for Health (C2H, as a member of INAHTA)
National Institute of Public Health (NIPH)

Chief, Division of Policy Evaluation, Department of Health Policy
National Centre for Child Health and Development, Japan

Dr. Eri Hoshino serves in dual roles in Japan's health research and policy landscape: as Head of the International Division at the Centre for Outcomes Research and Economic Evaluation for Health (C2H) within the National Institute of Public Health (NIPH), and as Chief of the Division of Policy Evaluation in the Department of Health Policy at the National Centre for Child Health and Development.

Research Focus: She focuses on Health Technology Assessment (HTA) with an emphasis on pediatric and maternal health. Her work includes health economic evaluation, cost-effectiveness analysis, quality of life assessment, and the development of patient-reported outcome measures. She has contributed to HTA methodology that considers diverse cultural perspectives and has experience in conducting systematic reviews and meta-analyses.

Notable Projects: She has participated in collaborative initiatives, including the AP-7D (Asia PBM seven dimensions) project, working with colleagues to develop a preference-based measure for East and Southeast Asian populations. She also contributes to East Asian research on caregiver well-being measurement, collaborating with partners in Taiwan and South Korea on culturally sensitive assessment tools. As part of research teams studying pediatric medications, she has supported evidence-based pediatric healthcare. She has also been involved in developing assessment approaches for newborn screening programs in Japan.

International Engagement: She participates in international HTA collaborations through networks such as HTAsiaLink, HTAi, and INAHTA, learning from colleagues and sharing experiences across borders.

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Dr. Izzuna Mudla Mohamed Ghazali

Public Health Physician/Deputy Director
Malaysian Health Technology Assessment Section (MaHTAS)
Medical Development Division
Ministry of Health Malaysia

Dr. Izzuna Mudla Mohamed Ghazali is a Public Health Physician and the Deputy Director of the Medical Development Division, Ministry of Health Malaysia. She leads the Malaysian Health Technology Assessment Section (MaHTAS). MaHTAS evaluates health technologies which includes medical devices, pharmaceuticals, biologics, medical and surgical procedures, public health interventions and digital technologies for decisions on reimbursement, clinical practice, procurement, pricing and service coverage.

Dr. Izzuna is actively involved at the local and international levels. She is member of the steering committee of i-CONNECT (Malaysia Collaborative Network for Innovation, Academy of Science Malaysia), and committee members of Healthtechhub Monitoring Committee, Nutritional Research, National Technology Innovation Sandbox, DRG Implementation Technical Committee, and the National Rare Disease Committee. At the international level, she is currently the Vice President of the International Health TechScan (i-HTS) (Health System Demands and Policy Integration), Past Chair of the International Society for Pharmacoeconomics and Outcome Research (ISPOR) HTA Roundtable Asia Pacific, Past-President of HTAsiaLink, and a member of the organizing committee for HTAi Asia Policy Forum.

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Prof. Sitanshu Sekhar Kar

Professor of Preventive and Social Medicine
Principal Investigator, Health Technology Assessment in India (HTAIn) Resource Hub
Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER)
India

Dr. Sitanshu Sekhar Kar is a Professor in the Department of Preventive and Social Medicine at Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India. He has around 20 years of academic and research experience in Public Health. He played an important role in starting the MPH programme at JIPMER and establishing JIPMER International School of Public Health (JISPH) and holds additional responsibility as officer-In-Charge of JISPH.

He is the principal investigator of the HTAIn Resource Hub established at JIPMER, Puducherry from 2020-21. He contributed to various research studies commissioned by the Department of Health Research, notably, EQ-5D-5L Value set generation and Estimation of cost-effective threshold for India. He also conducted the first health inequality aversion survey in Puducherry, India. He takes a special interest in the issues of health equity and adaptive HTA methods.

He is a Fulbright Nehru Academic Professional Excellence Fellow of 2016-17 at the University of Southern California Institute for Global Health, LA, USA. Prior to joining JIPMER in February 2010, he had served in the WHO Country Office for India and in the Population Council, New Delhi.

Dr Sitanshu was awarded for his research output at the national and regional levels. He has 210 publications for his credit in peer-reviewed journals. His areas of work include chronic disease epidemiology, Health technology assessment, Tobacco control and Medical Education.

Moderator

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A/Prof. Wanrudee Isaranuwatchai

Director
Health Intervention and Technology Assessment Program (HITAP)
Ministry of Public Health, Thailand

Dr. Wanrudee Isaranuwatchai is an Assistant Secretary-General and Senior Researcher of the Health Intervention and Technology Assessment Program Foundation (HITAP Foundation), Thailand. She is also an Affiliated Scientist at St. Michael’s Hospital, and an Associate Professor at the Institute of Health Policy, Management and Evaluation, University of Toronto, in Canada.

Her research focuses on how to apply health economics and health technology assessment (HTA) in the real-world setting as well as how to advance methods in economic evaluation (EE). She has experience conducting EEs using various methods with specific interest in the potential of big data in health economics and HTA to support evidence generation and policy-making process.

She has also collaborated with researchers, health professionals, and policy-makers in various areas to help communicate the value of health initiatives using EE. She has contributed to the training on HTA to support health systems in Asia, Africa, and North America. Dr. Isaranuwatchai is dedicated to the creation and use of evidence in healthcare decision making.

Sharing Session 1: Draft recommendations from the Lancet Commission for Strengthening the Use of Epidemiological Modelling of Emerging and Pandemic Infectious Diseases

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Prof. Alex Cook

Vice Dean (Research)
Saw Swee Hock School of Public Health

Dr Alex Cook is a Professor in the Saw Swee Hock School of Public Health (SSHSPH) at the National University of Singapore (NUS), where he is also the Vice Dean of Global Health, and the director of the Centre for Epidemic Research and Modelling. He also holds joint appointments at the Duke-NUS Medical School Singapore, at the Department of Statistics and Data Science, NUS, and the National Centre for Infectious Diseases, Singapore. He has been a faculty member at NUS since 2008, after three years working as a post-doc at the Department of Actuarial Mathematics and Statistics, Heriot-Watt University, and the Department of Plant Sciences, University of Cambridge.

His work uses quantitative methods such as infectious disease modelling and statistics to address public health problems, including dengue, COVID-19, influenza, diabetes and tobacco control. His team’s work—which has appeared in the national and international media, including the Straits Times, the Sunday Times, the Lianhe Zaobao, New Paper, Today, Reuters, Agence-France Presse, France 24, the Times of India, and Sky News—is often in close collaboration with government agencies, including in Singapore the Ministry of Health, the National Environment Agency, the Health Promotion Board and the Ministry of Defence, as well as with overseas partners. Examples of the contribution of his work to national policy making include:

  1. His team’s projections of the future burden of diabetes in Singapore was cited in the Committee of Supply as the Minister of Health declared ‘war’ on diabetes;
  2. His team’s work during the COVID-19 pandemic provided information to support government decisions in reopening society, border measures, and vaccination;
  3. His close collaboration with the National Environment Agency has led to the development of a realtime dengue forecasting algorithm that is routinely used as part of Singapore’s vector control programme.


His team’s work during the COVID-19 pandemic earned them the award of the President’s Certificate of Commendation, while he won the Pingat Pentadbiran Awam (Perak) (COVID-19) from the Prime Minister’s Office and the Mochtar Riady Pinnacle Award for research from the National University Health System. In addition to his research, Dr Cook has won several awards for his teaching, including two faculty teaching awards from the Faculty of Science, one from the SSHSPH, and one from the university.
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Prof. Mark Jit

School of Global Public Health
New York University

Mark Jit is professor and chair of the Department of Global and Environmental Health at New York University. He also holds honorary appointments at the London School of Hygiene & Tropical Medicine, the University of Hong Kong and the National University of Singapore. His research focuses on epidemiological and economic modelling of vaccines to support evidence-based public health decision making. He also organises or contributes to academic and professional courses on vaccine modelling, economics and decision science around the world.

Plenary 2: The Road Ahead: Navigating Possibilities with HTA

Panelists

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A/Prof. Chen Wen Jia

Saw Swee Hock School of Public Health

Dr. Chen Wenjia is an assistant professor at Saw Swee Hock School of Public Health, National University of Singapore since 2021. She obtained her PhD degree in Health Economics and Outcomes Research from University of British Columbia, Canada in 2016. With an ultimate goal to address the complexity of care and treatment in chronic diseases that ensures the sustainability of our healthcare system, Dr Chen’s research program aims to apply big data analytics to generate cutting-edge real-world evidence to support personalised, ‘systems’ care of chronic diseases and multi-morbidity. Her current projects include the development of AI-based clinical decision support e-tools for chronic respiratory conditions, economic evaluation of precision medicine and AI-empowered digital health technologies, prediction of policy influence on long-term economics of chronic respiratory disease. Recently, she has published important relevant papers in high impact clinical and policy journals, such as the 20-year individualized COPD risk predictor in Chest and methodological challenges in economic evaluation of precision medicine in Value in Health.

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Ms. Kelly Lenahan

Director
Global HTA Initiatives
Professional Society for Health Economics and Outcomes Research (ISPOR)

Kelly Lenahan is the Director of Global HTA Initiatives at ISPOR – the professional society for health economics and outcomes research. She has been responsible for all the global health technology assessment activities at ISPOR since 2015. She collaborates with local experts to hold HTA Roundtables in 5 major regions of the globe. Kelly has a passion for sharing information and helping to make connections globally, especially in low- and middle-income countries, to improve healthcare systems and health technology assessment processes. She received her Master’s in Public Health with a concentration in Epidemiology from Rutgers University. Kelly has several publications about coverage restrictions for specialty drugs in the United States and received a Rising Star award from the Healthcare Businesswomen’s Association.

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Prof. Mark Sculpher

Professor of Health Economics
University of York

Mark Sculpher is Professor of Health Economics and Director of the Centre for Health Economics, University of York. He is also Co-Director of the Policy Research Unit in Economic Evaluation of Health and Care Interventions, a programme of research for the UK Department of Health and Social Care funded by the National Institute for Health Research (NIHR).

Mark has worked in the field of economic evaluation and health technology assessment for over 30 years. He has researched in a range of clinical areas including heart disease, cancer, diagnostics, and public health. He has also contributed to research methods in the field, in particular relating to decision analytic modelling and techniques to handle uncertainty, heterogeneity and generalisability. He is also experienced in economic analysis in low- and middle-income settings. He has over 300 peer-reviewed publications and is a co-author of two major textbooks in the area: Methods for the Economic Evaluation of Health Care Programmes (OUP, 2015 with Drummond, Claxton, Torrance and Stoddart) and Decision Modelling for Health Economic Evaluation (OUP, 2006 with Briggs and Claxton).

Mark is an emeritus member of the UK NIHR College of Senior Investigators. He has been a member of the National Institute for Health and Care Excellence (NICE) Technology Appraisal Committee, the NICE Public Health Interventions Advisory Committee and NICE’s Diagnostics Advisory Committee. He has also been involved in advising NICE on methods over many years. Mark has also advised the UK House of Commons Health and Social Care Select Committee, as well as health systems internationally on health technology assessment methods including those in France, Ireland, Japan, Singapore, Germany, Portugal, Taiwan and New Zealand. He has been a member of the Commissioning Board for the UK NHS Health Technology Assessment Programme, the UK NIHR /Medical Research Council’s Methodology Research Panel and the UK Department of Health’s Policy Research Programme’s Commissioning Panel. He served as President of the International Society for Pharmacoeconomics and Outcomes Research (ISPOR) (2011-12). Mark is a Fellow of the UK Academy of Medical Sciences.

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Dr. Xiao Yue

Division Chief
National Center for Medicine and Health Technology Assessment of China

Yue Xiao, PhD in Management Science, Professor, senior Research Fellow, Director of the Research Unit on Application of Health Assessment & Evaluation, the China National Health Development Research Center, National Health Commission, P. R. China. Her research domains include application of evaluation and assessment in health reforms and development. She has promoted the development of HTA as a discipline as well as a system in China, and conducted quite a few key HTAs for the National Health Commission, covering medicines, medical devices, clinical procedures, and public health interventions, etc. She led the research and development of evaluation manuals on medicines and medical technologies, including artificial intelligence and medical equipment. She has worked as principal investigator or main investigator on over 60 national projects, including 5 major national science and technology development projects. She edited or coauthored 10 books, and published over 120 academic papers in key academic journals in Chinese and English.

Moderator

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A/Prof. Wee Hwee Lin

Director
Centre for Health Interventions and Policy Evaluation Research
Saw Swee Hock School of Public Health

Associate Professor Wee Hwee Lin is Director of the Centre for Health Intervention and Policy Evaluation Research (HIPER) based in the Saw Swee Hock School of Public Health at the National University of Singapore. HIPER develops capacity in health technology assessments in ASEAN through short courses and project mentoring. She is a member of the International Society for Pharmacoeconomics and Outcomes Research Health Sciences Policy Council, the International Editorial Advisory Board for Journal of Patient Reported Outcomes, and the National Advisory Committee on Cancer in Singapore. A/P Wee’s current work focuses on the use of real world evidence in health technology assessments. Specifically, this entails mining both structured and unstructured data in electronic medical records to evaluate cost-effectiveness of health technologies.

Plenary 3: Translating HTA Into Impactful Results: Value-Based Healthcare

Panelists

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Ms. Lin Liang

Head
Agency for Care Effectiveness
Ministry of Health, Singapore

Ms Lin Liang and her team conduct HTA and publish technology guidances on the clinical– and cost-effectiveness of health technologies supporting national funding decisions. To make healthcare more accessible, her team also engages manufacturers in value-based pricing negotiations to ensure prices are commensurate with the outcomes they deliver for patients and the Singapore health system.

She is currently the Head (HTA) at the Agency for Care Effectiveness, MOH, and holds an adjunct Assistant Professor position at Saw Swee Hock School of Public Health. She has published several systematic reviews and cost-effectiveness studies in peer-reviewed journals and holds an MSc in International HTA from the University of Sheffield.

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Dr. Wija Oortwijn

Senior Lecturer
Radboud University Medical Center


Chair, Insured Package Advisory Committee
National Health Care Institute, The Netherlands

Wija Oortwijn holds a position as senior lecturer in the field of global HTA at the Radboud University Medical Center (Radboudumc) and is Chair of the Insured Package Advisory (appraisal) Committee of the National Health Care Institute (ZIN) in the Netherlands. She studied health sciences and holds a PhD in Medicine (priority setting for HTA). She has more than 30 years of relevant professional experience in HTA and health policy analysis around the globe. Since 1992, she has been extensively involved in the development of HTA and health system strengthening around the world. She is a founding member of the Dutch Society for HTA (NVTAG) and the international HTA Society (HTAi). She is currently HTAi Board Member, Past President and associate editor of the International Journal of Technology Assessment in Health Care.

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Dr. Kavitha Rajsekar

Senior Scientist, Department of Health Research
Ministry of Health and Family Welfare, Government of India

  • Dr. Kavitha Rajsekar is a senior scientist (Scientist-F) of ICMR, Department of Health Research, Ministry of Health and Family Welfare, Government of India.
  • Hold a MSc, MPhil, PhD in Biochemistry and Molecular Biology from the University of Madras, India.
  • Coordinates the Health Technology assessment India Attached office in Department of Health Research- working actively for implementation of HTA for informed policy decisions in India.
  • Has large number of Publications in peer reviewed journals
  • Coordinates the DHR ICMR Advanced Molecular Oncology Diagnostic services (DIAMONDS) scheme
  • Drafted the Surrogacy Regulation Act 2021 which has been enacted in December 2021
  • Drafted the Assisted Reproductive Technology Regulation Act 2021 which has been enacted in December 2021
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Dr. Yot Teerawattananon

Secretary General
Health Intervention and Technology Assessment Program (HITAP)
Ministry of Public Health, Thailand

Yot Teerawattananon is the founder of the Health Intervention and Technology Assessment Program (HITAP) at the Thai Ministry of Public Health and a visiting professor at the Saw Swee Hock School of Public Health, National University of Singapore. He is also a co-founder of the Health Technology Assessment (HTA) network in Asia, known as HTAsiaLink, and the international Decision Support Initiative (iDSI).

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Dr. Joanne Yoong

ISPOR VBHC Task Force

Chief Executive Officer, Research for Impact

Dr Joanne Yoong is the founder and Chief Executive Officer of Research For Impact, a Singapore-based think-tank dedicated to making the behavioural and social sciences accessible, inclusive, and transformative for all. She is an applied micro-economist and interdisciplinary researcher working on consumer and household decision-making in vulnerable populations. Dr Yoong holds multiple faculty appointments and is the author of over ninety peer-reviewed articles in leading economics, medical and public health journals. Dr Yoong serves in various national and international policy and industry advisory capacities, is a member of the founding and organizing committee for the first Asian Workshop for Health Economics and Econometrics and is the president of the Singapore chapter of ISPOR—The Professional Society for Health Economics and Outcomes Research.

Dr Yoong received her PhD in Economics at Stanford University as an FSI Starr Foundation Fellow after an early career in financial services, and her AB summa cum laude in Economics and Applied and Computational Mathematics from Princeton University.

Moderator

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Dr. Huang Li-Ying (Grace)

Director
Division of Health Technology Assessment
Center for Drug Evaluation, Taiwan

Dr. Li Ying (Grace) Huang is a senior director and senior researcher at the Division of the Health Technology Assessment, Center for Drug Evaluation, Taiwan (CDE/HTA). Before joining CDE/HTA in 2008, she worked for 10 years as a clinical pharmacist in a leadership role in the department of pharmacy in one of the major medical centers in Taipei. She completed her Ph.D. degree in the Graduate Institute of Health Policy and Management, College of Public Health, National Taiwan University and a Master’s degree in pharmaceutical science from the National Taiwan University as well. She has authored and co-authored articles published in Health Policy, The Journal of Clinical Pharmacology, Journal of Nephrology, European Review for Medical and Pharmacological Sciences, and many others.

She also serves as a reviewer of manuscripts for several international journals. Her current research focuses on the comparative effectiveness of new drugs, applying mixed treatment comparison methods, the patient involved HTA, and therapeutic inertia among adult DM patients in Taiwan. She is honored to serve as the board of director at INAHTA from 2016 to 2018 and 2019 to 2021. She was also invited as a panelist in HTAi, INAHTA, ISPOR HTA Roundtable Asia Pacific, and CIRS workshops to share the experience of patient involvement in HTA, Development of Managed Entry Agreement (MEA) in Taiwan, HTA capacity building in the Asia region, and gain feedback from others.

Sharing Session 2: Valuation Survey of a new region-specific preference-based measure, AP-7D: One of the first PBM internationally developed in East and Southeast Asia

Panelists

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Dr. Yot Teerawattananon

Secretary General
Health Intervention and Technology Assessment Program (HITAP)
Ministry of Public Health, Thailand

Yot Teerawattananon is the founder of the Health Intervention and Technology Assessment Program (HITAP) at the Thai Ministry of Public Health and a visiting professor at the Saw Swee Hock School of Public Health, National University of Singapore. He is also a co-founder of the Health Technology Assessment (HTA) network in Asia, known as HTAsiaLink, and the international Decision Support Initiative (iDSI).

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Dr. Morii Yasuhiro

Center for Outcomes Research and Economic Evaluation for Health (C2H), Japan

Dr. Yasuhriro Morii serves in roles in Japan's health research and policy landscape: as a researcher and a member of the International Division at the Centre for Outcomes Research and Economic Evaluation for Health (C2H) within the National Institute of Public Health (NIPH). The work at C2H is dedicated to evaluating medical drugs and medical devices for the cost-effectiveness evaluation in Japan, research and human resource development in the field of HTA.

Research Focus: His research fields include health economic assessment, cost-effectiveness analysis, quality of life research, and the development of patient-reported outcome measures, health services research such as geographical accessibility and equity of healthcare resources allocation.

Notable Projects: He has participated in collaborative initiatives, including the AP-7D (Asia PBM seven dimensions) project, working with colleagues to develop a preference-based measure for East and Southeast Asian populations.

International Engagement: He participates in international HTA collaborations through networks such as HTAsiaLink, HTAi, and INAHTA, learning from colleagues and sharing experiences across borders.

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Prof. Jeonghoon Ahn

Ewha Womans University, Korea

Dr. Jeonghoon Ahn is a full professor at the Ewha Womans University (Seoul, Korea) and an adjunct fellow at the National Evidence-based healthcare Collaborating Agency (NECA), Seoul, Korea. He is an expert on health technology assessment (HTA) and health economics. He worked 7 years in NECA and served in various decision making and advisory committees of public agencies such as the Health Insurance Review and Assessment Services (HIRA) and the Korean Centers for Disease Control (KCDC). Professor Ahn has graduated the Seoul National University Department of International Economics for undergraduate and master program. He also received a PhD in Economics from the University of Southern California (USC) and was an assistant professor of pharmaceutical economics and Policy at the USC. Dr. Ahn has served on international professional organizations such as ISPOR, HTAi, INAHTA, and HTAsiaLink. He cofounded a regional HTA agency network, the HTAsiaLink (www.htasialink.org) with other regional experts.

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Dr. Nan Luo

Associate Professor
Saw Swee Hock School of Public Health

Dr Nan Luo is an Associate Professor in Saw Swee Hock School of Public Health (SSHSPH) and Yong Loo Lin School of Medicine at the National University of Singapore (NUS). Dr Luo’s main research interest and expertise is measurement of self-reported health status and well-being including patient-reported outcomes (PRO), health-related quality of life (HRQL), and health-state preferences. Dr Luo is internationally known for his research work on EQ-5D which is the mostly used HRQL instrument in health technology assessment worldwide.

Moderator

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Dr. Eri Hoshino

Head, International Division
Centre for Outcomes Research and Economic Evaluation for Health (C2H, as a member of INAHTA)
National Institute of Public Health (NIPH)

Chief, Division of Policy Evaluation, Department of Health Policy
National Centre for Child Health and Development, Japan

Dr. Eri Hoshino serves in dual roles in Japan's health research and policy landscape: as Head of the International Division at the Centre for Outcomes Research and Economic Evaluation for Health (C2H) within the National Institute of Public Health (NIPH), and as Chief of the Division of Policy Evaluation in the Department of Health Policy at the National Centre for Child Health and Development.

Research Focus: She focuses on Health Technology Assessment (HTA) with an emphasis on pediatric and maternal health. Her work includes health economic evaluation, cost-effectiveness analysis, quality of life assessment, and the development of patient-reported outcome measures. She has contributed to HTA methodology that considers diverse cultural perspectives and has experience in conducting systematic reviews and meta-analyses.

Notable Projects: She has participated in collaborative initiatives, including the AP-7D (Asia PBM seven dimensions) project, working with colleagues to develop a preference-based measure for East and Southeast Asian populations. She also contributes to East Asian research on caregiver well-being measurement, collaborating with partners in Taiwan and South Korea on culturally sensitive assessment tools. As part of research teams studying pediatric medications, she has supported evidence-based pediatric healthcare. She has also been involved in developing assessment approaches for newborn screening programs in Japan.

International Engagement: She participates in international HTA collaborations through networks such as HTAsiaLink, HTAi, and INAHTA, learning from colleagues and sharing experiences across borders.